FAM234B

Across TCGA cell cohorts, FAM234B mutation is significantly associated with the mutation status of many other genes, with 4,423 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM234B-associated genes across cancer lineages are TRIM67, WDR3, and APLP1. Each is linked with FAM234B in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM234B-to-partner and partner-to-FAM234B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRIM67 grouped by FAM234B-low versus FAM234B-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM234B→partner) and Y-score (partner→FAM234B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	TRIM67 →	+5.115	+5.115	.005	.005	1	4
BREAST	WDR3 →	+4.297	+4.857	.009	.009	1	3
BREAST	APLP1 →	+5.297	+5.297	.004	.004	1	3
BREAST	FAM184A →	+4.297	+4.857	.009	.009	1	3
BREAST	GHR →	+5.297	+5.297	.004	.004	1	3
PANCREAS	IL1RL2 →	+5.115	+5.115	.005	.005	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,423 associations by consensus.

TRIM67 by FAM234B expression — PANCREAS

Explore this box plot interactively →