FAM234A

Across TCGA pan-cancer cohorts, FAM234A mass-spec protein differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of FAM234A’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where FAM234A mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types FAM234A is over-expressed in tumor, although a few such as COAD and CCRCC show the opposite, repressed pattern.

COAD, CCRCC, and PDAC are the cancer types where FAM234A tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM234A mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	−0.491	<.001	9	view →
CCRCC	Male	All	−0.371	<.001	7	view →
PDAC	Female	All	−0.604	.004	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

FAM234A–COAD

Open the COAD breakdown →