FAM234A

Across TCGA patient cohorts, FAM234A protein abundance is significantly associated with the RNA expression of many other genes, with 7,012 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FAM234A-associated genes across cancer lineages are PLXNC1, LILRB3, and NFAM1. Each is linked with FAM234A in more than 4 cancer types. Because this analysis shows association rather than direction, both FAM234A-to-partner and partner-to-FAM234A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM234A versus PLXNC1 in GBM, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM234A→partner) and Y-score (partner→FAM234A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLXNC1 →	-0.704	-0.296	<.001	<.001	3	5
OV	LILRB3 →	-0.733	-0.554	.005	.002	3	5
LUAD	NFAM1 →	-0.646	-0.328	<.001	<.001	3	5
UCEC	CD1D →	-0.503	-0.243	<.001	.003	3	5
OV	JAML →	-1.080	-0.577	<.001	.001	3	5
UCEC	TMEM273 →	-0.788	-0.387	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,012 associations by consensus.

FAM234A vs PLXNC1 — GBM

Explore this scatter interactively →