FAM234A

Across TCGA patient cohorts, FAM234A mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM234A-associated genes across cancer lineages are INPP4B, PCNA, and ATM. Each is linked with FAM234A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM234A-to-partner and partner-to-FAM234A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by FAM234A-low versus FAM234A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM234A→partner) and Y-score (partner→FAM234A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.276	-1.700	.026	.040	3	2
UCEC	PCNA →	+0.251	+2.459	.002	.018	3	2
UCEC	ATM →	-0.608	-2.222	<.001	.010	3	2
UCEC	eEF2 →	+0.412	+2.321	.002	.033	3	1
UCEC	GAPDH →	+0.480	+2.459	.019	.018	3	1
UCEC	GATA6 →	-0.157	-2.307	.009	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

INPP4B by FAM234A expression — UCEC

Explore this box plot interactively →