FAM230E

Across TCGA patient cohorts, FAM230E mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM230E-associated genes across cancer lineages are RNA5SP482, RNU6-358P, and YPEL5P3. Each is linked with FAM230E in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM230E-to-partner and partner-to-FAM230E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP482 grouped by FAM230E-low versus FAM230E-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM230E→partner) and Y-score (partner→FAM230E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP482 →	+0.682	+5.081	.001	.008	3	1
UCEC	RNU6-358P →	+1.037	+5.133	<.001	.008	3	1
UCEC	YPEL5P3 →	+0.306	+5.420	<.001	.005	3	1
UCEC	ATP6V1G1P1 →	+0.247	+6.226	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

RNA5SP482 by FAM230E expression — UCEC

Explore this box plot interactively →