FAM230E

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, FAM230E RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of FAM230E’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where FAM230E RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FAM230E is over-expressed in tumor, although a few such as ESCA show the opposite, repressed pattern.

THCA and ESCA are the cancer types where FAM230E tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM230E RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
THCAAllAll+0.013<.0015view →
ESCAAllAll−0.021.0321view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

FAM230E–THCA

Tumor-vs-normal expression box plot for FAM230E RNA in THCA.

Open the THCA breakdown →

Exploration