Across TCGA patient cohorts, FAM230B mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM230B-associated genes across cancer lineages are PDCD4, A-Raf_pS299, and FOXO3a_pS318_S321. Each is linked with FAM230B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM230B-to-partner and partner-to-FAM230B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM230B→partner) and Y-score (partner→FAM230B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.388	-1.807	.046	.027	3	2
UCEC	A-Raf_pS299 →	-0.104	-2.459	.035	.019	3	1
UCEC	FOXO3a_pS318_S321 →	-0.120	-2.321	.019	.006	3	1
UCEC	ACC1 →	+0.399	+3.335	.007	.005	3	1
UCEC	p62 Lck ligand →	+0.354	+1.807	.008	.027	3	1
UCEC	ARID1A →	-0.180	-2.899	.019	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

FAM230B survival (RNA) · tumor vs normal (RNA) · all FAM230B data types