Across TCGA pan-cancer cohorts, FAM230B RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of FAM230B’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where FAM230B RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FAM230B is over-expressed in tumor.

THCA and UCEC are the cancer types where FAM230B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM230B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	+0.095	<.001	8	view →
UCEC	All	All	+0.003	.024	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: FAM230B RNA expression & survival · all FAM230B data types