FAM230A

Across TCGA patient cohorts, FAM230A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,344 significant associations in total. STAD shows the largest number of these associations.

The most reproducible FAM230A-associated GO terms across cancer lineages are Regulation of membrane invagination, Regulation of aspartic-type peptidase activity, and Regulation of ubiquitin-dependent protein catabolic process. Each is linked with FAM230A in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM230A-to-partner and partner-to-FAM230A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of membrane invagination grouped by FAM230A-low versus FAM230A-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM230A→partner) and Y-score (partner→FAM230A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of membrane invagination →	+0.073	+0.012	<.001	.003	3	3
STAD	Regulation of aspartic-type peptidase activity →	+0.094	+0.010	<.001	.002	3	3
STAD	Regulation of ubiquitin-dependent protein catabolic process →	+0.129	+0.015	<.001	<.001	3	3
STAD	Positive regulation of ubiquitin-dependent protein catabolic process →	+0.123	+0.008	<.001	<.001	3	3
STAD	Steroid biosynthetic process →	+0.080	+0.015	<.001	<.001	3	3
STAD	Regulation of hydrogen peroxide metabolic process →	+0.085	+0.009	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,344 associations by consensus.

Regulation of membrane invagination by FAM230A expression — STAD

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