FAM227B

Across TCGA patient cohorts, FAM227B protein abundance is significantly associated with the RNA expression of many other genes, with 541 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FAM227B-associated genes across cancer lineages are NEFH, ETV7, and CSF2RB. Each is linked with FAM227B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM227B-to-partner and partner-to-FAM227B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM227B versus NEFH in PDAC, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM227B→partner) and Y-score (partner→FAM227B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	NEFH →	-0.182	-0.540	.009	.005	3	1
PDAC	ETV7 →	+0.684	+0.730	<.001	<.001	3	1
PDAC	CSF2RB →	+0.891	+0.816	<.001	<.001	3	1
PDAC	IL2RB →	+0.721	+0.850	.001	.003	3	1
PDAC	PSME2 →	+0.466	+0.730	<.001	<.001	3	1
PDAC	TNFSF13B →	+0.691	+0.788	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 541 associations by consensus.

FAM227B vs NEFH — PDAC

Explore this scatter interactively →