FAM227B

Across TCGA patient cohorts, FAM227B mutation is significantly associated with the RNA expression of many other genes, with 2,368 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM227B-associated genes across cancer lineages are LINC00929, RNU6-909P, and LINC02281. Each is linked with FAM227B in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM227B-to-partner and partner-to-FAM227B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00929 grouped by FAM227B-low versus FAM227B-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM227B→partner) and Y-score (partner→FAM227B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	LINC00929 →	+0.122	+5.268	<.001	.006	3	3
BRCA	RNU6-909P →	+0.721	+5.473	<.001	.005	3	2
LIHC	LINC02281 →	+0.112	+5.647	<.001	.004	3	2
LIHC	MIR548D2 →	+0.391	+5.355	.007	.005	3	2
READ	RNU6-522P →	+0.732	+5.096	<.001	.002	3	2
READ	GMNC →	+0.248	+3.855	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,368 associations by consensus.

LINC00929 by FAM227B expression — LIHC

Explore this box plot interactively →