FAM227B

Across TCGA cell cohorts, FAM227B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,016 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM227B-associated GO terms across cancer lineages are Vesicle budding from membrane, Vesicle coating, and Intraciliary anterograde transport. Each is linked with FAM227B in more than 10 cancer types. Because this analysis shows association rather than direction, both FAM227B-to-partner and partner-to-FAM227B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle budding from membrane grouped by FAM227B-low versus FAM227B-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM227B→partner) and Y-score (partner→FAM227B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Vesicle budding from membrane →	+0.061	+0.761	<.001	<.001	3	10
OESOPHAGUS	Vesicle coating →	+0.074	+0.931	.002	<.001	2	11
LUNG_NSCLC_LUSC	Intraciliary anterograde transport →	+0.075	+0.765	<.001	.001	3	10
LIVER	Protein localization to cilium →	+0.073	+1.268	<.001	<.001	3	10
URINARY_TRACT	Ubiquitin-dependent protein catabolic process via the C-end degron rule pathway →	+0.063	+0.953	.002	.003	3	9
UPPER_AERODIGESTIVE_TRACT	Cytoplasmic translation →	+0.084	+0.667	.005	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,016 associations by consensus.

Vesicle budding from membrane by FAM227B expression — CNS

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