FAM226B

Across TCGA patient cohorts, FAM226B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,273 significant associations in total. STAD shows the largest number of these associations.

The most reproducible FAM226B-associated GO terms across cancer lineages are Positive regulation of oligodendrocyte differentiation, Obsolete histone modification, and tRNA methylation. Each is linked with FAM226B in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM226B-to-partner and partner-to-FAM226B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of oligodendrocyte differentiation grouped by FAM226B-low versus FAM226B-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM226B→partner) and Y-score (partner→FAM226B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Positive regulation of oligodendrocyte differentiation →	+0.062	+0.023	<.001	<.001	3	3
COAD	Obsolete histone modification →	+0.062	+0.003	<.001	<.001	3	3
COAD	tRNA methylation →	+0.037	+0.003	.002	<.001	3	3
COAD	Regulation of microtubule polymerization or depolymerization →	+0.034	+0.002	<.001	.004	3	3
STAD	Mitochondrial translation →	+0.053	+0.014	<.001	.006	3	3
COAD	Regulation of microtubule-based process →	+0.032	+0.003	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,273 associations by consensus.

Positive regulation of oligodendrocyte differentiation by FAM226B expression — LAML

Explore this box plot interactively →