FAM223B

Across TCGA patient cohorts, FAM223B RNA expression is significantly associated with the protein abundance of many other proteins, with 1,760 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FAM223B-associated proteins across cancer lineages are RABGGTA, TRA2B_T33, and RGS12_S16. Each is linked with FAM223B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM223B-to-partner and partner-to-FAM223B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM223B versus RABGGTA in COAD, with a Pearson correlation of -0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM223B→partner) and Y-score (partner→FAM223B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RABGGTA →	-0.210	-0.062	.002	.004	3	2
OV	TRA2B_T33 →	+1.175	+0.113	.003	.004	3	2
BRCA	RGS12_S16 →	+0.512	+0.157	.001	.007	3	2
OV	ASL →	-0.373	-0.147	.002	.003	3	2
LUAD	CHMP6_S119 →	+0.516	+0.060	<.001	.004	3	2
BRCA	PLCB3_S1105 →	+0.601	+0.104	.007	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,760 associations by consensus.

FAM223B vs RABGGTA — COAD

Explore this scatter interactively →