FAM223A

Across TCGA patient cohorts, FAM223A RNA expression is significantly associated with the go_rna of many other GO terms, with 1,467 significant associations in total. STAD shows the largest number of these associations.

The most reproducible FAM223A-associated GO terms across cancer lineages are Positive regulation of lipid biosynthetic process, Alditol metabolic process, and Iron ion transport. Each is linked with FAM223A in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM223A-to-partner and partner-to-FAM223A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of lipid biosynthetic process grouped by FAM223A-low versus FAM223A-high in KIRC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM223A→partner) and Y-score (partner→FAM223A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	Positive regulation of lipid biosynthetic process →	+0.033	+0.007	.001	<.001	3	3
UCEC	Alditol metabolic process →	+0.044	+0.008	<.001	<.001	3	3
PAAD	Iron ion transport →	+0.035	+0.010	.004	.002	3	2
LGG	Relaxation of vascular associated smooth muscle →	-0.045	-0.012	<.001	<.001	3	2
STAD	Negative regulation of mRNA processing →	+0.037	+0.045	.001	<.001	3	2
PAAD	Regulation of reproductive process →	+0.022	+0.025	.003	.001	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,467 associations by consensus.

Positive regulation of lipid biosynthetic process by FAM223A expression — KIRC

Explore this box plot interactively →