FAM222A

Across TCGA patient cohorts, FAM222A protein abundance is significantly associated with the RNA expression of many other genes, with 10,840 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM222A-associated genes across cancer lineages are NCAPD2, MAGOHB, and EMG1. Each is linked with FAM222A in more than 4 cancer types. Because this analysis shows association rather than direction, both FAM222A-to-partner and partner-to-FAM222A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM222A versus NCAPD2 in HNSC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM222A→partner) and Y-score (partner→FAM222A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NCAPD2 →	+0.987	+0.432	<.001	<.001	3	5
HNSC	MAGOHB →	+0.707	+0.336	<.001	.001	3	5
BRCA	EMG1 →	+0.648	+0.427	<.001	<.001	3	5
BRCA	NDUFA9 →	+0.486	+0.444	.003	<.001	3	5
LSCC	ZNF384 →	+0.586	+0.396	<.001	<.001	3	4
HNSC	MLF2 →	+0.703	+0.271	.001	.001	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,840 associations by consensus.

FAM222A vs NCAPD2 — HNSC

Explore this scatter interactively →