FAM222A

Across TCGA cell cohorts, FAM222A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,330 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FAM222A-associated GO terms across cancer lineages are Regulation of DNA repair, Urokinase plasminogen activator signaling pathway, and Regulation of double-strand break repair via homologous recombination. Each is linked with FAM222A in more than 13 cancer types. Because this analysis shows association rather than direction, both FAM222A-to-partner and partner-to-FAM222A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA repair grouped by FAM222A-low versus FAM222A-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM222A→partner) and Y-score (partner→FAM222A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of DNA repair →	+0.063	+1.732	.001	<.001	3	14
LIVER	Urokinase plasminogen activator signaling pathway →	-1.161	-2.002	.002	<.001	3	13
SOFT_TISSUE	Regulation of double-strand break repair via homologous recombination →	+0.116	+1.521	<.001	<.001	3	13
SKIN	Vertebrate eye-specific patterning →	-1.089	-1.120	.003	.001	3	12
SOFT_TISSUE	Mitotic DNA replication →	+0.152	+1.058	.001	.001	3	12
SOFT_TISSUE	Positive regulation of DNA repair →	+0.096	+1.521	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,330 associations by consensus.

Regulation of DNA repair by FAM222A expression — LIVER

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