FAM221B

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM221B RNA expression is significantly associated with the protein abundance of many other proteins, with 10,214 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM221B-associated proteins across cancer lineages are RIN1, COLGALT1, and PRXL2B. Each is linked with FAM221B in more than 4 cancer types. Because this analysis shows association rather than direction, both FAM221B-to-partner and partner-to-FAM221B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM221B→partner) and Y-score (partner→FAM221B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCRIN1 →-0.572-0.236<.001.00535
GBMCOLGALT1 →-0.529-0.293<.001<.00134
BRCAPRXL2B →+0.329+0.240<.001<.00133
GBMTFAM →+0.408+0.341<.001<.00133
GBMMIA3_S727 →-0.564-0.244<.001<.00133
HNSCMYO1E →-0.387-0.215<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,214 associations by consensus.

Exploration