Across TCGA cell cohorts, FAM221B RNA expression is significantly associated with the RNA expression of many other genes, with 6,717 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FAM221B-associated genes across cancer lineages are RABL2A, CCDC183, and CACFD1. Each is linked with FAM221B in more than 7 cancer types. Because this analysis shows association rather than direction, both FAM221B-to-partner and partner-to-FAM221B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM221B→partner) and Y-score (partner→FAM221B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	RABL2A →	+1.126	+0.035	<.001	.001	2	8
BREAST	CCDC183 →	+1.340	+0.298	<.001	<.001	2	7
BREAST	CACFD1 →	+1.961	+0.323	<.001	<.001	3	6
BREAST	PNPLA7 →	+1.423	+0.239	<.001	<.001	3	6
SOFT_TISSUE	KHDC4 →	+0.924	+0.023	<.001	<.001	3	6
LUNG_SCLC	BBS1 →	+0.792	+0.070	.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,717 associations by consensus.

Exploration

FAM221B survival (RNA) · tumor vs normal (RNA) · all FAM221B data types