FAM220A

Across TCGA cell cohorts, FAM220A mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM220A-associated genes across cancer lineages are GYPB and OTOS. Each is linked with FAM220A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM220A-to-partner and partner-to-FAM220A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GYPB grouped by FAM220A-low versus FAM220A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM220A→partner) and Y-score (partner→FAM220A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GYPB →	+0.107	+4.977	<.001	.007	3	1
BLOOD_Leukemia	OTOS →	+0.039	+4.969	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

GYPB by FAM220A expression — LARGE_INTESTINE

Explore this box plot interactively →