FAM21EP

Across TCGA patient cohorts, FAM21EP RNA expression is significantly associated with the go_rna of many other GO terms, with 6,999 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible FAM21EP-associated GO terms across cancer lineages are Base-excision repair, AP site formation, Endoplasmic reticulum tubular network formation, and Positive regulation of DNA repair. Each is linked with FAM21EP in more than 18 cancer types. Because this analysis shows association rather than direction, both FAM21EP-to-partner and partner-to-FAM21EP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Base-excision repair, AP site formation grouped by FAM21EP-low versus FAM21EP-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM21EP→partner) and Y-score (partner→FAM21EP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Base-excision repair, AP site formation →	+0.048	+0.275	.001	<.001	3	19
UCS	Endoplasmic reticulum tubular network formation →	+0.085	+0.224	<.001	.003	3	18
STAD	Positive regulation of DNA repair →	+0.039	+0.113	<.001	<.001	3	18
STAD	tRNA metabolic process →	+0.039	+0.157	<.001	<.001	3	18
STAD	RNA modification →	+0.039	+0.173	<.001	<.001	3	18
STAD	Protein localization to mitochondrion →	+0.038	+0.135	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,999 associations by consensus.

Base-excision repair, AP site formation by FAM21EP expression — ESCA

Explore this box plot interactively →