FAM219B

Across TCGA patient cohorts, FAM219B protein abundance is significantly associated with the RNA expression of many other genes, with 1,476 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FAM219B-associated genes across cancer lineages are GSDMB, ITGB5, and ENDOD1. Each is linked with FAM219B in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM219B-to-partner and partner-to-FAM219B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM219B versus GSDMB in PDAC, with a Pearson correlation of -0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM219B→partner) and Y-score (partner→FAM219B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	GSDMB →	-0.655	-0.855	.002	.004	3	3
GBM	ITGB5 →	+0.926	+0.350	.001	.004	3	3
UCEC	ENDOD1 →	+1.164	+0.430	.002	.002	3	2
UCEC	RNU6-1306P →	-2.007	-0.362	<.001	.007	3	2
UCEC	PLCXD2 →	-0.941	-0.387	.002	.007	3	2
UCEC	MADD-AS1 →	-0.806	-0.357	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,476 associations by consensus.

FAM219B vs GSDMB — PDAC

Explore this scatter interactively →