FAM218A

Across TCGA patient cohorts, FAM218A RNA expression is significantly associated with the protein abundance of many other proteins, with 11,478 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible FAM218A-associated proteins across cancer lineages are UCHL1, SP140L_S180, and TMEM154. Each is linked with FAM218A in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM218A-to-partner and partner-to-FAM218A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM218A versus UCHL1 in LSCC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM218A→partner) and Y-score (partner→FAM218A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UCHL1 →	+1.075	+0.598	<.001	<.001	3	4
GBM	SP140L_S180 →	-0.535	-0.602	.003	.005	3	3
GBM	TMEM154 →	-0.710	-0.761	.007	.001	3	3
GBM	PCGF2 →	+0.373	+0.582	.001	.003	3	3
HNSC	PNP →	-0.290	-0.573	<.001	.007	3	3
CCRCC	PPP1R1A_S67 →	+0.861	+0.583	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,478 associations by consensus.

FAM218A vs UCHL1 — LSCC

Explore this scatter interactively →