FAM218A

Across TCGA patient cohorts, FAM218A mutation is significantly associated with the RNA expression of many other genes, with 2,916 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM218A-associated genes across cancer lineages are RPL22P14, LINC00921, and ABALON. Each is linked with FAM218A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM218A-to-partner and partner-to-FAM218A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL22P14 grouped by FAM218A-low versus FAM218A-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM218A→partner) and Y-score (partner→FAM218A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RPL22P14 →	+0.171	+3.496	<.001	.008	3	2
UCEC	LINC00921 →	-0.231	-1.672	.003	.008	3	1
UCEC	ABALON →	+0.587	+2.491	<.001	<.001	3	1
LIHC	RNU7-179P →	+0.373	+5.149	<.001	.003	3	1
LIHC	NATP →	+0.256	+4.415	<.001	.006	3	1
LIHC	CYCSP29 →	+0.074	+5.149	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,916 associations by consensus.

RPL22P14 by FAM218A expression — COAD

Explore this box plot interactively →