FAM218A

Across TCGA cell cohorts, FAM218A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,558 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible FAM218A-associated GO terms across cancer lineages are Inorganic cation import across plasma membrane, Inorganic ion import across plasma membrane, and Cardiac muscle cell contraction. Each is linked with FAM218A in more than 9 cancer types. Because this analysis shows association rather than direction, both FAM218A-to-partner and partner-to-FAM218A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Inorganic cation import across plasma membrane grouped by FAM218A-low versus FAM218A-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM218A→partner) and Y-score (partner→FAM218A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Inorganic cation import across plasma membrane →	-0.080	-0.562	.001	<.001	3	10
URINARY_TRACT	Inorganic ion import across plasma membrane →	-0.080	-0.562	.001	<.001	3	10
PANCREAS	Cardiac muscle cell contraction →	-0.114	-0.501	<.001	<.001	3	8
OVARY	Cardiac muscle cell action potential involved in contraction →	-0.112	-0.428	<.001	<.001	3	7
STOMACH	Sodium ion transmembrane transport →	-0.052	-0.306	.003	.006	3	7
SKIN	Transcription initiation at RNA polymerase II promoter →	+0.059	+0.585	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,558 associations by consensus.

Inorganic cation import across plasma membrane by FAM218A expression — URINARY_TRACT

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