FAM218A

Across TCGA cell cohorts, FAM218A mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. CNS shows the largest number of these associations.

The most reproducible FAM218A-associated genes across cancer lineages are CDX4 and CLEC6A. Each is linked with FAM218A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM218A-to-partner and partner-to-FAM218A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDX4 grouped by FAM218A-low versus FAM218A-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM218A→partner) and Y-score (partner→FAM218A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	CDX4 →	+0.013	+6.357	<.001	<.001	3	1
CNS	CLEC6A →	+0.012	+5.321	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CDX4 by FAM218A expression — CNS

Explore this box plot interactively →