FAM217B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM217B mutation is significantly associated with the RNA expression of many other genes, with 1,786 significant associations in total. COAD shows the largest number of these associations.

The most reproducible FAM217B-associated genes across cancer lineages are CDCA2, NDUFA6, and MAPK12. Each is linked with FAM217B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM217B-to-partner and partner-to-FAM217B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM217B→partner) and Y-score (partner→FAM217B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADCDCA2 →+0.615+3.183.006.00932
COADNDUFA6 →+0.595+3.740<.001<.00132
COADMAPK12 →+0.761+3.489<.001.00232
COADGTF2E2 →+0.445+3.469.007.00232
COADANKRD39 →+0.393+3.200<.001.00932
COADARHGAP19 →+0.376+2.700.005.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,786 associations by consensus.

Exploration