FAM217A

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM217A RNA expression is significantly associated with the protein abundance of many other proteins, with 9,581 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM217A-associated proteins across cancer lineages are TRRAP, UBAP2L, and UBTF. Each is linked with FAM217A in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM217A-to-partner and partner-to-FAM217A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM217A versus TRRAP in LSCC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM217A→partner) and Y-score (partner→FAM217A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCTRRAP →+0.211+0.329<.001.00134
LUADUBAP2L →+0.217+0.430<.001<.00134
GBMUBTF →+0.320+0.285.001.00134
LSCCWRNIP1 →+0.271+0.334<.001<.00134
LUADWRNIP1_S75 →+0.748+0.439.001.00134
GBMXRN2 →+0.224+0.233.008.00534
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,581 associations by consensus.

FAM217A vs TRRAP — LSCC

Per-sample scatter of FAM217A vs TRRAP in LSCC (Pearson r = 0.40).

Explore this scatter interactively →

Exploration