FAM214BP1

Across TCGA pan-cancer cohorts, FAM214BP1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated FAM214BP1 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher FAM214BP1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FAM214BP1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and HNSC show a favorable association.

THCA, LUAD, and KIRC are the cancer types where FAM214BP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	II,III,IV	0.707	0.930	<.001	66	view →
LUAD	OS	Tertile	II,III,IV	0.779	0.477	.002	60	view →
KIRC	OS	Median	All	0.553	0.731	<.001	50	view →
HNSC	DFS	Quartile	All	0.807	0.675	.007	47	view →
READ	DFS	Tertile	IV	0.156	0.727	<.001	42	view →
SKCM	OS	Tertile	All	0.472	0.264	<.001	38	view →
TGCT	OS	Tertile	III,IV	0.003	1.000	<.001	36	view →
UCEC	OS	Tertile	IV	0.198	0.570	.003	36	view →
LGG	DFS	Tertile	All	0.566	0.764	<.001	36	view →
LIHC	DFS	Tertile	III,IV	0.566	0.134	.014	24	view →
ESCA	DFS	Median	III,IV	0.481	0.217	.001	21	view →
PAAD	OS	Median	II,III,IV	0.679	0.453	.005	21	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

FAM214BP1–THCA (OS)

Open the THCA breakdown →