FAM214BP1

Across TCGA pan-cancer cohorts, FAM214BP1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of FAM214BP1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where FAM214BP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FAM214BP1 is over-expressed in tumor, although a few such as LUSC and BLCA show the opposite, repressed pattern.

KIRC, HNSC, and LUSC are the cancer types where FAM214BP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM214BP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+0.027	<.001	9	view →
HNSC	All	All	+0.026	.010	6	view →
LUSC	All	All	−0.072	<.001	4	view →
BLCA	Female	III,IV	−0.028	.021	3	view →
THCA	Female	All	−0.305	<.001	2	view →
STAD	All	II,III,IV	+0.100	.024	2	view →
PAAD	Male	All	−0.065	.005	2	view →
KICH	Male	All	−0.038	.037	1	view →
BRCA	All	II,III,IV	+0.021	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

FAM214BP1–KIRC

Open the KIRC breakdown →