FAM214A

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM214A RNA expression is significantly associated with the protein abundance of many other proteins, with 14,788 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FAM214A-associated proteins across cancer lineages are PDCD4, TTI1, and OBI1_S210. Each is linked with FAM214A in more than 4 cancer types. Because this analysis shows association rather than direction, both FAM214A-to-partner and partner-to-FAM214A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM214A versus PDCD4 in UCEC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM214A→partner) and Y-score (partner→FAM214A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPDCD4 →+0.383+0.446<.001.00135
PDACTTI1 →-0.244-0.350.001<.00135
BRCAOBI1_S210 →-1.119-1.269<.001<.00134
BRCAWDR46 →-0.403-1.167<.001<.00134
BRCAU2SURP_S485 →-1.003-0.987<.001<.00134
BRCAZFYVE19 →+0.293+1.367<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,788 associations by consensus.

FAM214A vs PDCD4 — UCEC

Per-sample scatter of FAM214A vs PDCD4 in UCEC (Pearson r = 0.34).

Explore this scatter interactively →

Exploration