FAM214A

Across TCGA cell cohorts, FAM214A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,871 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FAM214A-associated GO terms across cancer lineages are Macroautophagy, Endoplasmic reticulum to cytosol transport, and Retrograde protein transport, ER to cytosol. Each is linked with FAM214A in more than 15 cancer types. Because this analysis shows association rather than direction, both FAM214A-to-partner and partner-to-FAM214A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macroautophagy grouped by FAM214A-low versus FAM214A-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM214A→partner) and Y-score (partner→FAM214A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Macroautophagy →	+0.091	+1.505	<.001	<.001	3	16
BONE	Endoplasmic reticulum to cytosol transport →	+0.128	+1.019	<.001	<.001	3	14
BONE	Retrograde protein transport, ER to cytosol →	+0.128	+1.019	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.099	-0.990	.007	.003	3	14
STOMACH	Golgi vesicle transport →	+0.065	+1.239	.001	<.001	3	14
STOMACH	Vacuole organization →	+0.066	+1.497	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,871 associations by consensus.

Macroautophagy by FAM214A expression — STOMACH

Explore this box plot interactively →