FAM210A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM210A mutation is significantly associated with the RNA expression of many other genes, with 111 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM210A-associated genes across cancer lineages are OR10Q2P, GUSBP15, and FAM74A7. Each is linked with FAM210A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM210A-to-partner and partner-to-FAM210A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10Q2P grouped by FAM210A-low versus FAM210A-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM210A→partner) and Y-score (partner→FAM210A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAOR10Q2P →+0.093+6.064<.001.00232
LUSCGUSBP15 →+0.449+5.211<.001.00732
BRCAFAM74A7 →+0.091+5.883<.001.00331
READCDRT15P8 →+0.125+5.421<.001.00531
UCECIL13 →+0.166+3.277<.001.00831
UCECIGHV3OR16-8 →+0.810+3.691.005.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 111 associations by consensus.

OR10Q2P by FAM210A expression — BRCA

Box plot of OR10Q2P in FAM210A-low vs FAM210A-high samples in BRCA.

Explore this box plot interactively →

Exploration