FAM209A

Across TCGA patient cohorts, FAM209A mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM209A-associated genes across cancer lineages are Rab25, ASNS, and BRCA2. Each is linked with FAM209A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM209A-to-partner and partner-to-FAM209A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rab25 grouped by FAM209A-low versus FAM209A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM209A→partner) and Y-score (partner→FAM209A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rab25 →	-0.428	-2.999	.007	.035	3	1
UCEC	ASNS →	+0.420	+3.000	.016	.036	3	1
UCEC	BRCA2 →	-0.133	-2.448	.029	.019	3	1
UCEC	Caspase-7-cleavedD198 →	+0.650	+2.189	.023	.034	3	1
UCEC	Cyclin-B1 →	+0.665	+2.321	.014	.034	3	1
UCEC	Heregulin →	-0.178	-3.169	.002	.019	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Rab25 by FAM209A expression — UCEC

Explore this box plot interactively →