FAM205BP

Across TCGA patient cohorts, FAM205BP mutation is significantly associated with the RNA expression of many other genes, with 3,698 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM205BP-associated genes across cancer lineages are FKBP3, EMC9, and GLA. Each is linked with FAM205BP in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM205BP-to-partner and partner-to-FAM205BP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FKBP3 grouped by FAM205BP-low versus FAM205BP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM205BP→partner) and Y-score (partner→FAM205BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FKBP3 →	+0.481	+1.799	.002	.001	3	2
UCEC	EMC9 →	+0.340	+2.609	.007	<.001	3	2
UCEC	GLA →	+0.481	+2.960	<.001	<.001	3	2
UCEC	R3HCC1 →	+0.515	+3.839	<.001	<.001	3	2
UCEC	BCCIP →	+0.466	+3.222	<.001	<.001	3	2
UCEC	KIF20A →	+0.539	+2.415	.005	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,698 associations by consensus.

FKBP3 by FAM205BP expression — UCEC

Explore this box plot interactively →