FAM205BP

Across TCGA pan-cancer cohorts, FAM205BP RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of FAM205BP’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where FAM205BP RNA is repressed in tumor relative to normal tissue. In most cancer types FAM205BP is over-expressed in tumor, although a few such as BRCA and UCEC show the opposite, repressed pattern.

BRCA, UCEC, and KIRP are the cancer types where FAM205BP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM205BP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	III,IV	−0.031	<.001	6	view →
UCEC	All	III,IV	−0.018	.032	4	view →
KIRP	All	II,III,IV	−0.008	.019	4	view →
KIRC	All	All	+0.008	.005	3	view →
LUSC	All	All	+0.024	.043	2	view →
KICH	All	II,III,IV	−0.009	.036	2	view →
LIHC	Male	All	+0.004	.019	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

FAM205BP–BRCA

Open the BRCA breakdown →