Across TCGA pan-cancer cohorts, FAM204DP RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of FAM204DP’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where FAM204DP RNA is repressed in tumor relative to normal tissue. In most cancer types FAM204DP is over-expressed in tumor, although a few such as STAD show the opposite, repressed pattern.
STAD are the cancer types where FAM204DP tumor–normal differential expression is most reproducible.