Across TCGA patient cohorts, FAM200A mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM200A-associated genes across cancer lineages are EGFR_pY1068, 14-3-3_beta, and eEF2. Each is linked with FAM200A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM200A-to-partner and partner-to-FAM200A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM200A→partner) and Y-score (partner→FAM200A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.260	-2.459	.008	.018	3	2
UCEC	14-3-3_beta →	-0.095	-2.973	.015	.035	3	1
UCEC	eEF2 →	+0.307	+2.000	.028	.010	3	1
UCEC	eIF4E →	+0.178	+3.013	.032	.018	3	1
UCEC	A-Raf_pS299 →	-0.125	-2.321	.007	.034	3	1
UCEC	ERK2 →	+0.226	+2.000	.002	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

FAM200A survival (RNA) · tumor vs normal (RNA) · all FAM200A data types