FAM199X

Across TCGA patient cohorts, FAM199X mutation is significantly associated with the RNA expression of many other genes, with 898 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM199X-associated genes across cancer lineages are RPL36AP35, MIR8059, and STAU2P1. Each is linked with FAM199X in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM199X-to-partner and partner-to-FAM199X results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL36AP35 grouped by FAM199X-low versus FAM199X-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM199X→partner) and Y-score (partner→FAM199X) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RPL36AP35 →	+0.184	+7.640	<.001	.009	3	2
UCEC	MIR8059 →	+0.322	+2.386	.001	.002	3	2
UCEC	STAU2P1 →	+0.133	+1.837	.001	.003	3	2
CESC	MIR4510 →	+0.297	+5.342	<.001	.002	3	2
CESC	RN7SL366P →	+0.082	+5.837	<.001	.001	3	2
LUAD	RNU6-20P →	+0.388	+3.336	.006	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 898 associations by consensus.

RPL36AP35 by FAM199X expression — BLCA

Explore this box plot interactively →