FAM199X

Across TCGA cell cohorts, FAM199X RNA expression is significantly associated with the go_rna of many other GO terms, with 3,406 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM199X-associated GO terms across cancer lineages are Random inactivation of X chromosome, Establishment of mitotic sister chromatid cohesion, and Phosphatidylinositol metabolic process. Each is linked with FAM199X in more than 12 cancer types. Because this analysis shows association rather than direction, both FAM199X-to-partner and partner-to-FAM199X results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Random inactivation of X chromosome grouped by FAM199X-low versus FAM199X-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM199X→partner) and Y-score (partner→FAM199X) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Random inactivation of X chromosome →	+0.104	+0.563	.005	.004	3	13
URINARY_TRACT	Establishment of mitotic sister chromatid cohesion →	+0.132	+0.781	.009	.005	3	12
OVARY	Phosphatidylinositol metabolic process →	+0.047	+0.735	<.001	<.001	3	12
OVARY	Regulation of protein ubiquitination →	+0.069	+0.718	<.001	<.001	3	12
OVARY	Negative regulation of post-transcriptional gene silencing →	+0.104	+0.538	.003	.003	3	11
OVARY	Negative regulation of miRNA-mediated gene silencing →	+0.104	+0.538	.003	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,406 associations by consensus.

Random inactivation of X chromosome by FAM199X expression — BONE

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