FAM199X

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FAM199X mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM199X-associated genes across cancer lineages are SIRPD and OR13G1. Each is linked with FAM199X in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM199X-to-partner and partner-to-FAM199X results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SIRPD grouped by FAM199X-low versus FAM199X-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM199X→partner) and Y-score (partner→FAM199X) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINESIRPD →+0.021+4.977<.001.00731
LARGE_INTESTINEOR13G1 →+0.032+5.415<.001.00431
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

SIRPD by FAM199X expression — LARGE_INTESTINE

Box plot of SIRPD in FAM199X-low vs FAM199X-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration