FAM198B-AS1

Across TCGA pan-cancer cohorts, FAM198B-AS1 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated FAM198B-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher FAM198B-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FAM198B-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and ACC show a favorable association.

HNSC, KIRP, and UCS are the cancer types where FAM198B-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.696	0.803	.002	93	view →
KIRP	DFS	Quartile	All	0.361	0.852	<.001	67	view →
UCS	OS	Median	IV	0.817	0.302	.002	44	view →
LGG	OS	Median	All	0.371	0.510	<.001	36	view →
ACC	OS	Quartile	III,IV	0.813	0.265	.001	34	view →
GBM	DFS	Tertile	All	0.178	0.464	.001	33	view →
CESC	DFS	Quartile	All	0.433	0.768	<.001	32	view →
BRCA	DFS	Median	III,IV	0.934	0.818	.002	26	view →
READ	DFS	Tertile	IV	0.244	0.750	.001	25	view →
UVM	OS	Median	III,IV	0.281	1.000	.003	24	view →
LUAD	OS	Quartile	II,III,IV	0.870	0.620	.002	21	view →
KIRC	DFS	Quartile	All	0.884	0.738	.004	20	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

FAM198B-AS1–HNSC (OS)

Open the HNSC breakdown →