FAM198B-AS1

Across TCGA pan-cancer cohorts, FAM198B-AS1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of FAM198B-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where FAM198B-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FAM198B-AS1 is over-expressed in tumor, although a few such as UCEC and BRCA show the opposite, repressed pattern.

KIRC, UCEC, and HNSC are the cancer types where FAM198B-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM198B-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.290	<.001	7	view →
UCEC	All	All	−1.393	<.001	6	view →
HNSC	All	III,IV	+0.374	.008	6	view →
LUAD	All	All	+0.338	.001	6	view →
KICH	All	All	+0.970	.001	5	view →
BRCA	Female	All	−0.420	.004	4	view →
PRAD	All	All	+1.034	<.001	2	view →
STAD	Male	All	+0.532	.026	2	view →
LUSC	Male	II,III,IV	−0.321	.010	2	view →
CHOL	All	All	+0.287	.002	2	view →
LIHC	All	All	+0.077	.026	2	view →
KIRP	All	All	−0.136	.016	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

FAM198B-AS1–KIRC

Open the KIRC breakdown →