FAM193B

Across TCGA patient cohorts, FAM193B RNA expression is significantly associated with the go_rna of many other GO terms, with 7,168 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible FAM193B-associated GO terms across cancer lineages are Positive regulation of DNA repair, Obsolete histone methylation, and Negative regulation of DNA-templated transcription, elongation. Each is linked with FAM193B in more than 31 cancer types. Because this analysis shows association rather than direction, both FAM193B-to-partner and partner-to-FAM193B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by FAM193B-low versus FAM193B-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM193B→partner) and Y-score (partner→FAM193B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Positive regulation of DNA repair →	+0.065	+0.736	<.001	<.001	3	32
SCLC	Obsolete histone methylation →	+0.127	+0.637	<.001	<.001	3	31
SCLC	Negative regulation of DNA-templated transcription, elongation →	+0.104	+0.725	<.001	<.001	3	31
SCLC	Positive regulation of double-strand break repair via homologous recombination →	+0.103	+0.759	<.001	<.001	3	31
STAD	Organelle transport along microtubule →	+0.056	+0.655	<.001	<.001	3	30
SCLC	Positive regulation of double-strand break repair →	+0.083	+0.660	<.001	<.001	3	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,168 associations by consensus.

Positive regulation of DNA repair by FAM193B expression — SCLC

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