FAM193B

Across TCGA pan-cancer cohorts, FAM193B RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of FAM193B’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where FAM193B RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FAM193B is over-expressed in tumor, although a few such as BRCA and KICH show the opposite, repressed pattern.

KIRC, COAD, and LIHC are the cancer types where FAM193B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM193B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	+1.354	<.001	12	view →
COAD	Male	II,III,IV	+0.658	<.001	10	view →
LIHC	Female	II,III,IV	+1.452	<.001	9	view →
BRCA	Female	All	−0.481	<.001	4	view →
CHOL	All	All	+2.451	<.001	3	view →
KICH	All	All	−0.475	.006	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

FAM193B–KIRC

Open the KIRC breakdown →