FAM193B

Across TCGA patient cohorts, FAM193B mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM193B-associated genes across cancer lineages are ASNS, JNK_pT183_Y185, and p62 Lck ligand. Each is linked with FAM193B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM193B-to-partner and partner-to-FAM193B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by FAM193B-low versus FAM193B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM193B→partner) and Y-score (partner→FAM193B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.647	+2.584	<.001	.010	3	2
UCEC	JNK_pT183_Y185 →	-0.179	-3.169	.012	.018	3	1
UCEC	p62 Lck ligand →	+0.467	+2.710	<.001	.003	3	1
UCEC	PCNA →	+0.274	+3.169	.002	.018	3	1
UCEC	Annexin-1 →	+0.837	+2.479	<.001	.010	3	1
UCEC	Rictor_pT1135 →	-0.113	-3.321	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

ASNS by FAM193B expression — UCEC

Explore this box plot interactively →