FAM193B

Across TCGA cell cohorts, FAM193B mutation is significantly associated with the RNA expression of many other genes, with 675 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM193B-associated genes across cancer lineages are DTWD2, ARMC2, and NUDT6. Each is linked with FAM193B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM193B-to-partner and partner-to-FAM193B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DTWD2 grouped by FAM193B-low versus FAM193B-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM193B→partner) and Y-score (partner→FAM193B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	DTWD2 →	+0.841	+3.199	<.001	.007	3	2
LARGE_INTESTINE	ARMC2 →	+0.434	+3.237	.004	.003	3	2
LARGE_INTESTINE	NUDT6 →	+0.696	+3.234	.003	.004	3	2
LARGE_INTESTINE	ZMYND10 →	+0.470	+3.321	<.001	.003	3	2
LARGE_INTESTINE	EXD2 →	+0.469	+3.180	.007	.004	3	2
OESOPHAGUS	CCDC140 →	+0.198	+4.017	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 675 associations by consensus.

DTWD2 by FAM193B expression — BLOOD_Leukemia

Explore this box plot interactively →