FAM193A

Across TCGA patient cohorts, FAM193A mutation is significantly associated with the RNA expression of many other genes, with 2,990 significant associations in total. COAD shows the largest number of these associations.

The most reproducible FAM193A-associated genes across cancer lineages are STRA6, DOC2B, and CHCHD4. Each is linked with FAM193A in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM193A-to-partner and partner-to-FAM193A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, STRA6 grouped by FAM193A-low versus FAM193A-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM193A→partner) and Y-score (partner→FAM193A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	STRA6 →	-1.286	-3.385	.001	<.001	3	4
UCEC	DOC2B →	-0.878	-2.370	<.001	<.001	3	4
CESC	CHCHD4 →	+0.638	+3.184	<.001	.009	3	4
COAD	WNT5B →	-0.798	-3.700	<.001	.001	3	4
COAD	THUMPD3 →	+0.396	+3.352	.003	.005	3	4
UCEC	EIF1AD →	+0.226	+1.554	.004	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,990 associations by consensus.

STRA6 by FAM193A expression — SKCM

Explore this box plot interactively →