FAM193A

Across TCGA cell cohorts, FAM193A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,889 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM193A-associated GO terms across cancer lineages are Transcription pausing by RNA polymerase II, Regulation of aggrephagy, and Positive regulation of double-strand break repair. Each is linked with FAM193A in more than 18 cancer types. Because this analysis shows association rather than direction, both FAM193A-to-partner and partner-to-FAM193A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription pausing by RNA polymerase II grouped by FAM193A-low versus FAM193A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM193A→partner) and Y-score (partner→FAM193A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Transcription pausing by RNA polymerase II →	+0.166	+0.757	<.001	<.001	3	19
LUNG_NSCLC_LUSC	Regulation of aggrephagy →	+0.177	+0.945	<.001	.002	3	18
BREAST	Positive regulation of double-strand break repair →	+0.072	+0.913	<.001	<.001	3	16
BONE	Epigenetic regulation of gene expression →	+0.087	+0.971	<.001	<.001	3	16
URINARY_TRACT	Positive regulation of cilium assembly →	+0.108	+1.041	<.001	<.001	3	16
STOMACH	Negative regulation of gene expression, epigenetic →	+0.085	+0.725	.003	.007	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,889 associations by consensus.

Transcription pausing by RNA polymerase II by FAM193A expression — BONE

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