FAM193A

Across TCGA cell cohorts, FAM193A mutation is significantly associated with the RNA expression of many other genes, with 1,805 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM193A-associated genes across cancer lineages are IDI2, CPLX4, and GFRA4. Each is linked with FAM193A in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM193A-to-partner and partner-to-FAM193A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IDI2 grouped by FAM193A-low versus FAM193A-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM193A→partner) and Y-score (partner→FAM193A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	IDI2 →	+0.021	+2.859	<.001	.008	3	3
OVARY	CPLX4 →	+0.034	+3.906	<.001	.001	3	2
BLOOD_Leukemia	GFRA4 →	+0.226	+3.824	.003	.001	3	2
BLOOD_Leukemia	OR13J1 →	+0.205	+3.774	<.001	.008	3	2
LUNG_NSCLC_LUAD	PITX2 →	+1.311	+3.279	.006	.005	3	2
LARGE_INTESTINE	TADA2B →	+0.615	+2.158	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,805 associations by consensus.

IDI2 by FAM193A expression — OVARY

Explore this box plot interactively →